Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1978-2-18
pubmed:abstractText
To investigate the nature of variations in the large intestine potential differences, a continuous perfusion of isotonic saline was carried out in the colon of 14 rats. Intraluminal pressure and potential differences between the lumen and the peritoneal cavity were continuously and simultaneously recorded, while impedance of the system and respiration were also constantly monitored. To obtain a quantitative evaluation of the data, Fast Fouier Transform was performed on the signals and their derivatives which were auto- and cross-correlated. While there was no obvious relation between pressure and potential in the unperfused colon, there was clear visual qualirative evidence that, during steady state conditions of perfusion, an increase in intraluminal pressure was accompanied by a decrease in potential differences, while impedance of the recording system remained unchanged. Computer analysis disclosed four narrow ranges of stable frequencies for both pressure and potential. They were centred around 0-3, 1-75, 10-7, and 75 cycles per minute, the latter being synchronous with respiration. It is concluded that the variations of potential differences recorded during perfusion, a well-know phenomenon, are not electrical artefacts: the fast rhythm is probably induced by respiration, which increases intracolonic pressure and that, in turn, reduces the absolute value of potential differences, which remain negative mucosa versus serosa. The slower rhythms are synchronous for pressure and potential. Mechanisms responsible for the decrease in potential related to the increase in pressure remain unknown.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-1186325, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-13631076, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-4430469, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-4573443, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-4729202, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-4851168, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-4885397, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5358583, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5435266, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5439136, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5555785, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5639361, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5764598, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-5787112, http://linkedlifedata.com/resource/pubmed/commentcorrection/590835-765185
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0017-5749
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
771-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Correlation of variations in intraluminal pressure and potential differences in the perfused colen.
pubmed:publicationType
Journal Article