Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
1966-6-16
pubmed:abstractText
Macrogranulocytic and/or erythroid megaloblastic bone marrow changes which could not be accurately predicted from the hematologic findings in the blood were present in 25% of 305 mildly to moderately anemic pregnant women attending a public antepartum clinic in Montreal. Iron deficiency was the primary cause of anemia in most instances. Serum folate activity of less than 4.1 ng./ml. and/or serum vitamin B(12) levels of less than 100 pg./ml. were present in 90% of the 77 patients having these bone marrow changes, whereas approximately one-third of 228 patients with normoblastic marrow had these low values. Red cell folate did not correlate as well as serum folate activity with bone marrow changes. After treatment with oral folic acid in the range of 0.2 mg. to 0.8 mg., daily, for seven to 14 days, the megaloblastic and macrogranulocytic changes in patients with low serum folate activity and normal serum vitamin B(12) values disappeared in 15 of 21 patients. Of five women having both low folate and vitamin B(12) values, three failed to respond and two showed only partial improvement after 0.4 mg. of folic acid daily, per os, for 10 days. The average diet of these anemic women was suboptimal in folate and in iron.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13017432, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13268516, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13332461, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13402240, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13403989, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13416992, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13519192, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13536254, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13542323, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13669036, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13686103, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13687521, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13703914, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13705279, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13713522, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13744982, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13764898, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13881119, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13895866, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13902309, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13952598, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13953900, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13953904, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-13978088, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14117224, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14149944, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14236726, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14238675, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14353575, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14401212, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14414776, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14418552, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-14938452, http://linkedlifedata.com/resource/pubmed/commentcorrection/5907944-5830026
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0008-4409
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
636-45
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1966
pubmed:articleTitle
Nutritional anemia and megaloblastosis in pregnancy.
pubmed:publicationType
Journal Article, In Vitro