Linked Life Data

59078

Source:http://linkedlifedata.com/resource/pubmed/id/59078

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7975
pubmed:dateCreated
1976-8-23
pubmed:abstractText
Tetraparental mouse chimaeras formed by aggregation of early embryos have been utilised in the study of immunological mechanisms. Tolerance in chimaeras has proven somewhat controversial, but recent evidence has suggested the existence of "classic" tolerance and furthermore that this is achieved by elimination of cells potentially capable of fatal self in equilibrium self reactivity. Clonal elimination was also considered to be responsible for the "correction" of the autoimmune disease of NZB mice made chimaeric with a normal strain. It is now suggested that a similar mechanism may be responsible for the "normal" elimination of any aberrant autoimmune clone in both mouse and man.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
20-1
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
"Normal" elimination of aberrant autoimmune clones.
pubmed:publicationType
Journal Article