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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1966-5-21
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pubmed:abstractText |
1. Fibrin clots obtained from diluted human plasma with bovine thrombin often contain amounts of phospholipids that cannot be diminished by further plasma dilution. 2. The ;cold insoluble residue' obtained during fibrinogen preparation has a higher phosphorus content than the purified fibrinogen. 3. Evidence showed that adsorption of phospholipids or phosphorus-containing fibrinopeptides on purified fibrinogen or fibrin was unlikely. 4. O-Phosphorylserine was detected in acid hydrolysates of human fibrin. 5. On the basis of phosphorus determinations the average molecular weight of human fibrinogen cannot be less than 342000 (304000-383000) for a group of ten donors, and 265000 for two other persons, assuming 1 phosphorus atom/molecule and incomplete splitting of the phosphorus-containing fibrinopeptide. Complete splitting of the phosphopeptide would require molecular weights twice as high. 6. Fibrinolysis was a possible cause of lower phosphorus contents found in isolated fibrinogen and fibrin from a donor who showed apprehension during blood collection and in a fibrinogen preparation that had been submitted to prolonged dialysis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-13018207,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-13159917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-13249966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-13471508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-13522663,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-13971745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-14080867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-14363242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-16746620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-16747230,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5862426-16748065
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0264-6021
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
886-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading | |
pubmed:year |
1965
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pubmed:articleTitle |
Molecular weight of human fibrinogen derived from phosphorus determinations.
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pubmed:publicationType |
Journal Article,
In Vitro
|