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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1980-4-17
|
| pubmed:abstractText |
The efficacy of seven more recently developed anthelmintics of the benzimidazolecarbamate group, i. e., parbendazole, mebendazole, fenbendazole, oxibendazole, cambendazole, oxfendazole and albendazole, has been tested in a series of experiments on white mice artifically infected with Trichinella spiralis. Our results disclosed a relationship between their anthelmintic effect and their chemical structure. This finding might be of importance in a targeted synthesis of new, effective, derivates of benzimidazole, e. g., in the therapy of trichinellosis and in the choice of the most effective drug.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0015-5683
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
145-9
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:583335-Animals,
pubmed-meshheading:583335-Benzimidazoles,
pubmed-meshheading:583335-Cambendazole,
pubmed-meshheading:583335-Fenbendazole,
pubmed-meshheading:583335-Mebendazole,
pubmed-meshheading:583335-Mice,
pubmed-meshheading:583335-Structure-Activity Relationship,
pubmed-meshheading:583335-Trichinella,
pubmed-meshheading:583335-Trichinellosis
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Relationship between the antitrichinellous effect of seven derivates of benzimidazolecarbamates and their chemical structure.
|
| pubmed:publicationType |
Journal Article
|