Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1977-11-25
pubmed:abstractText
The lung lesions produced by multiple short-term intratracheal instillations of saline solutions of sodium zirconium lactate (NaZL), zirconium-aluminum-glycine hydroxychloride complex (ZAG), and aluminum chlorhydrate (ACH) in hamsters were studied by light and electron microscopy. These solutions produced lesions beginning with exudative pneumonia followed by pneumonitis (interstitial pneumonia) and foreign body granulomas. Electron microscopic microprobe analysis demonstrated the metallic component of the instilled compounds in membrane-bound cytoplasmic inclusions of macrophages. The lesions produced by NaZL and ZAG were similar to those produced by ACH. These lesions were also similar to those in previous reports of aerosol exposure of animals to zirconium or aluminum, or to other unrelated compounds.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0003-9985
pubmed:author
pubmed:issnType
Print
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
545-9
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Acute lung lesions due to zirconium and aluminum compounds in hamsters.
pubmed:publicationType
Journal Article