Linked Life Data

578473

Source:http://linkedlifedata.com/resource/pubmed/id/578473

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1977-10-31
pubmed:abstractText
The subacute and chronic toxicity of 2,6-xylidide of 2-pyridone-3-carboxylic acid (isonixine), a non-steroidal analgesic-anti-inflammatory agent, was investigated in male rabbits and in rats of both sexes, respectively, after oral administration. Isonixine was very well tolerated by the two species studied and only at the dose of 2000 mg/kg presented some mild toxic effects after 6 months of daily treatment. It is worthwhile to note that isonixine did not induce any gastro-intestinal lesion even after repeated oral administration for periods up to 6 months at 2000 mg/kg.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1460-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Toxicological investigations of isonixine.
pubmed:publicationType
Journal Article