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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1980-3-17
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pubmed:abstractText |
One component (rearing) of the stereotyped behavior of the rat was quantitated using erigometer, a new device developed in this laboratory. Intraperitoneal injection of atropine, but not methylatropine, caused dose-related stereotyped behavior in the rat and this effect was antagonized by intracaudate injection of triperidol in a dose-related manner. It is concluded that stereotypy can be evoked also in the case when the striatal dopaminergic tone is normal or even below normal: it is the equilibrium of the striatal cholinergic-dopaminergic systems which must be shifted towards dopamine, which is necessary for the development of this behavioral manifestation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0301-0244
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
277-81
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:574956-Animals,
pubmed-meshheading:574956-Atropine,
pubmed-meshheading:574956-Behavior,
pubmed-meshheading:574956-Caudate Nucleus,
pubmed-meshheading:574956-Dose-Response Relationship, Drug,
pubmed-meshheading:574956-Humans,
pubmed-meshheading:574956-Injections,
pubmed-meshheading:574956-Rats,
pubmed-meshheading:574956-Stereotyped Behavior,
pubmed-meshheading:574956-Trifluperidol
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pubmed:articleTitle |
Atropine stereotypy and its inhibition by intracaudate triperidol in the rat.
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pubmed:publicationType |
Journal Article
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