Linked Life Data

573354

Source:http://linkedlifedata.com/resource/pubmed/id/573354

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1979-11-29
pubmed:abstractText
The tumor-stroma junction of invasive squamous cell carcinoma of the larynx was examined electron microscopically. Polymorphic cytoplasmic protrusions (blebs) with a diameter ranging from 2--4 micron to 8--10 micron were observed on the basal and lateral surfaces of the malignant keratinocytes. A system of cytoplasmic 6--8 nm microfilaments can be seen consistently at the base of the blebs. The microfilaments possibly serve as a contractile ring during the pinching-off process of the blebs from the malignant keratinocytes. The blebs were observed at various stages of development until the pinching-off process occurred. They have varying shapes, sizes, and electron density and are plasmamembrane bounded. They contain hyaline ectoplasm, ribosome particles, a fine filamentous and fine granular material as well as some lysosomes. The blebbing phenomenon is discussed in respect to the cellular locomotion of malignant keratinocytes and interpreted as a possible temporary invasion mechanism in the preliminary stages of the tumor growth.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0340-1588
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
575-82
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
[Ultrastructure of tumor-stroma junction of invasive laryngeal carcinoma (author's transl)].
pubmed:publicationType
Journal Article, English Abstract