Linked Life Data

5717544

Source:http://linkedlifedata.com/resource/pubmed/id/5717544

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1969-5-15
pubmed:abstractText
Small nodules are commonly seen in the rectal mucosa during sigmoidoscopy of patients over 40 years of age and are often noted in rectums excised for carcinoma. There is little information in the literature on the pathology of these small nodules. There is evidence that there are various histological types which are possibly of different clinical significance. This problem has been studied using a series of rectums removed surgically for carcinoma and a comparable series of rectums obtained at necropsy from subjects with no evidence of large bowel disease. The incidence, distribution, and histological structure of nodules more than 1 mm in diameter has been studied. The commonest histological types of lesion are found to be adenomas and metaplastic nodules. The histological structure, mode of formation, natural history, and clinical significance of metaplastic nodules is considered in detail. It is concluded that metaplastic nodules are a normal finding in the rectal mucosa of subjects over 40 years old. It is suggested that they represent an aging change in the mucosa. They are easily distinguished histologically from adenomas and evidence is presented that they have no relation to them and are not liable to undergo malignant change.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-9746
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
735-43
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1968
pubmed:articleTitle
Structure and significance of metaplastic nodules in the rectal mucosa.
pubmed:publicationType
Journal Article