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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1976-7-6
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pubmed:abstractText |
Incubation of human platelets in plasma containing a suspension of latex particles for 1-90 min resulted in progressive accumulation of particles in the open-channel system, followed by localization of latex in electron-opaque vacuoles. After 60 min, acid phosphatase was localized within latex-containing vacuoles. The periodate-alkaline-bismuth reaction intensely stained external membranes and membranes of the open-channel system. Membranes of latex-containing organelles were not stained. Latex phagocytosis was independent of both anticoagulant choice and aspirin effects. Our results indicate that the platelet can act as a true phagocyte, and we suggest that the phagocytic process is chronologically similar to that reported for polymorphonuclear leukocytes.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0006-4971
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
47
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
833-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:56961-Acid Phosphatase,
pubmed-meshheading:56961-Bismuth,
pubmed-meshheading:56961-Blood Platelets,
pubmed-meshheading:56961-Cell Membrane,
pubmed-meshheading:56961-Humans,
pubmed-meshheading:56961-Latex,
pubmed-meshheading:56961-Microspheres,
pubmed-meshheading:56961-Periodic Acid,
pubmed-meshheading:56961-Phagocytosis,
pubmed-meshheading:56961-Staining and Labeling,
pubmed-meshheading:56961-Vacuoles
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pubmed:year |
1976
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pubmed:articleTitle |
Phagocytosis in human platelets: localization of acid phosphatase-positive phagosomes following latex uptake.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
|