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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5612
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pubmed:dateCreated |
1968-9-9
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pubmed:abstractText |
A study has been performed on the effect of Norinyl-1 and Ortho-Novin, two low-dose oral contraceptives, on blood-clotting factors. Ortho-Novin contains twice the amount of hormone as Norinyl-1. It was therefore possible to observe whether any changes detected were related to the dose of oestrogen-progestin combination. The women were tested in parallel with matched normal female controls and a group in the third trimester of pregnancy. Significant rises in factor VII and X levels were found with both low-dose preparations from the third month onwards. There was no difference between patients on Norinyl-1 and Ortho-Novin, and hence the clotting changes do not appear to be dose-dependent. The long-term effects on clotting factors of these low-dose oral contraceptive preparations remain to be investigated.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral,
http://linkedlifedata.com/resource/pubmed/chemical/Factor VII,
http://linkedlifedata.com/resource/pubmed/chemical/Factor X,
http://linkedlifedata.com/resource/pubmed/chemical/Mestranol,
http://linkedlifedata.com/resource/pubmed/chemical/Norethindrone
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0007-1447
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
218-21
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pubmed:dateRevised |
2010-10-26
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pubmed:meshHeading |
pubmed-meshheading:5662975-Blood Coagulation,
pubmed-meshheading:5662975-Contraceptives, Oral,
pubmed-meshheading:5662975-Factor VII,
pubmed-meshheading:5662975-Factor X,
pubmed-meshheading:5662975-Female,
pubmed-meshheading:5662975-Humans,
pubmed-meshheading:5662975-Mestranol,
pubmed-meshheading:5662975-Norethindrone,
pubmed-meshheading:5662975-Prothrombin Time
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pubmed:year |
1968
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pubmed:articleTitle |
Effects of low-dose oral contraceptives on blood coagulation.
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pubmed:publicationType |
Journal Article
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