rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1968-5-9
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pubmed:abstractText |
1. Extracts from Moraxella lwoffi oxidize propionate, but at a low rate when compared with whole cells. 2. This oxidative activity requires the formation of propionyl-CoA. 3. Enzymes catalysing the formation of propionyl phosphate and propionyl-CoA are present. The presence of a propionyl-CoA hydrolase is considered to be an artifact, but partly responsible for the low rates of oxidation. 4. Enzymes catalysing the reduction of NAD(+) and the formation of pyruvate with propionyl-CoA as substrate are also present. 5. That the only pathway for the metabolism of propionate in extracts is a direct one to acetate via pyruvate was confirmed by the use of (14)C-labelled materials. 6. A possible sequence of enzyme-catalysed reactions that will account for the experimental observations is described.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-13035025,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-13105682,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-13152052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-13546163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-13610881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-13628525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-14270123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-14292829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-14803460,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-14908008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5642619-4296055
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-28
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:5642619-Acetates,
pubmed-meshheading:5642619-Acyltransferases,
pubmed-meshheading:5642619-Carbon Isotopes,
pubmed-meshheading:5642619-Cell-Free System,
pubmed-meshheading:5642619-Coenzyme A,
pubmed-meshheading:5642619-Esterases,
pubmed-meshheading:5642619-Keto Acids,
pubmed-meshheading:5642619-Models, Biological,
pubmed-meshheading:5642619-Moraxella,
pubmed-meshheading:5642619-Oxidation-Reduction,
pubmed-meshheading:5642619-Oxygen Consumption,
pubmed-meshheading:5642619-Phosphotransferases,
pubmed-meshheading:5642619-Propionates,
pubmed-meshheading:5642619-Pyruvates
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pubmed:year |
1968
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pubmed:articleTitle |
A direct pathway for the metabolism of propionate in cell extracts from Moraxella lwoffi.
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pubmed:publicationType |
Journal Article
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