Linked Life Data

5579263

Source:http://linkedlifedata.com/resource/pubmed/id/5579263

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1971-7-20
pubmed:abstractText
The sterol content and composition of the small intestinal muccsa has been studied in the rat, guinea pig, and rabbit. In the three species, noncholesterol sterols formed a large proportion of the total sterol content. In the rat, the contribution due to plant sterols was much smaller than in the guinea pig and rabbit, but in all three species the amount of campesterol present seemed disproportionately large compared with beta-sitosterol. These observations are presented as evidence that the intestinal mucosa is able to discriminate in its uptake of sterols from the lumen. The presence of plant sterol at all levels of the intestine makes it clear that luminal sterols can be taken up throughout the small bowel, but the data suggest that the upper intestine is the major site of sterol uptake. In the rat, the sterol composition of the intraluminal contents was also studied after its separation by ultracentrifugation into an aqueous (or micellar) phase and a sediment. Examination of the content and composition of the intraluminal sterols at different levels of the intestine provided support for the idea that the major site of cholesterol absorption was in the upper small intestine. The major part of the intraluminal sterol was found in the sediment; precipitation did not, however, render sterols unavailable for absorption and the micellar sterols reflected closely the pattern found in the corresponding sediment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-2275
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
336-46
pubmed:dateRevised
2007-3-20
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
Sterols in the small intestine of the rat, guinea pig, and rabbit.
pubmed:publicationType
Journal Article