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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
5756
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pubmed:dateCreated |
1971-6-19
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|
pubmed:abstractText |
An in-vivo skin perfusion technique has been used to study the pharmacological activity in inflamed skin of patients with allergic contact eczema. Perfusates from 35 out of 45 patients contained a smooth-muscle-contracting agent with prostaglandin-like properties. Solvent partition followed by thinlayer chromatography revealed this activity to be due to a mixture of prostaglandins E and F. This direct evidence supports the view that prostaglandins mediate inflammation in man.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0007-1447
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
|
|
pubmed:volume |
2
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
258-60
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pubmed:dateRevised |
2010-10-26
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pubmed:meshHeading |
pubmed-meshheading:5572386-Animals,
pubmed-meshheading:5572386-Chromatography, Thin Layer,
pubmed-meshheading:5572386-Dermatitis, Contact,
pubmed-meshheading:5572386-Eczema,
pubmed-meshheading:5572386-Fatty Acids,
pubmed-meshheading:5572386-Guinea Pigs,
pubmed-meshheading:5572386-Humans,
pubmed-meshheading:5572386-Muscle, Smooth,
pubmed-meshheading:5572386-Muscle Contraction,
pubmed-meshheading:5572386-Perfusion,
pubmed-meshheading:5572386-Prostaglandins,
pubmed-meshheading:5572386-Rats
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pubmed:year |
1971
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pubmed:articleTitle |
Recovery of prostaglandins in human cutaneous inflammation.
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pubmed:publicationType |
Journal Article,
In Vitro
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