Linked Life Data

556916

Source:http://linkedlifedata.com/resource/pubmed/id/556916

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-3-31
pubmed:abstractText
The anesthetic partial pressure causing a loss of righting reflex in mice (ED50) was determined for isoflurane at ambient total pressures ranging from 1 to 100 atmospheres absolute (ATA). The higher pressures, produced by adding helium, decreased isoflurane's apparent anesthetic effect: 48 percent more was needed at 100 ATA. This is consistent with previous work with N2O, where a 46 percent increase was found. The ED50 for isoflurane at 1 ATA is 0.0057 ATA, only 29 percent of that predicted by the Meyer-Overton relationship for mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-2999
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-101
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Isoflurane anesthesia and pressure antagonism in mice.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.