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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1977-3-21
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pubmed:abstractText |
Physostigmine was given to 12 patients with various spincerebellar degenerations, and neurologic examinations were recorded on video tapes and assessed on a semiquantitative scale. Forty minutes after a single dose, the scores improved by 35.7 +/- 4.7 percent (means +/- SEM). Eight patients were then studied over sequential 3-month periods by a randomized double-blind trial of physostigmine versus placebo. With physostigmine, scores were 33.9 +/- 8.3 percent better than before treatment or with placebo. Further investigations of cholinergic drugs seem warranted in patients with these diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
70-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:556821-Ataxia,
pubmed-meshheading:556821-Cerebellar Ataxia,
pubmed-meshheading:556821-Child,
pubmed-meshheading:556821-Female,
pubmed-meshheading:556821-Friedreich Ataxia,
pubmed-meshheading:556821-Humans,
pubmed-meshheading:556821-Male,
pubmed-meshheading:556821-Myoclonic Cerebellar Dyssynergia,
pubmed-meshheading:556821-Physostigmine,
pubmed-meshheading:556821-Time Factors
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pubmed:year |
1977
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pubmed:articleTitle |
Physostigmine in familial ataxias.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
|