Linked Life Data

553975

Source:http://linkedlifedata.com/resource/pubmed/id/553975

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-3-17
pubmed:abstractText
A series of experiments leading towards the field trial of an irradiated blood-derived vaccine against Babesia divergens, common cause of redwater in cattle in Europe, is described. Initially a number of isolates of B. divergens were made from the blood of sick animals in a variety of localities in the british Isles. These isolates were cryopreserved and then characterised by inoculation into groups of spenectomised Friesian calves, whose reactions were statistically analysed. Attempts were made to prepare a vaccine against B. divergens infection using diluted infected blood, but when these failed it was found that irradiation of infected blood within the range of 24 to 32 kilorads and its intravenous inoculation into calves produced the required immune response without pathogenic effects. An irradiated blood-derived vaccine produced by the irradiation of infected blood at 25 or 30 kilorads was used in a field trial in Ireland, and vaccinated calves were protected against a field challenge which caused redwater in 10 control cattle, six of which had severe reactions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1019-9128
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
339-44
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Bovine babesiosis: steps towards an irradiated vaccine.
pubmed:publicationType
Journal Article