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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1976-3-20
|
| pubmed:abstractText |
Severe extensive alopecia areata (totalis) was treated with prednisolone as a single 2 g dose i.v. (22 patients) or 0.5 g daily for 5 days orally (13 patients). Four of the patients responded well, 12 had a poor response and 19 had no response. There was a relapse in some at about 6 months, which could be arrested by a further single i.v. dose, but the risks of this form of therapy are unclear and it cannot be recommended for general use. The clinical response to a single dose of corticosteroid implies, however, that there may be a 'switch' mechanism in certain auto-immune diseases, with an all-or-none response.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0001-5555
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
493-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:55045-Administration, Oral,
pubmed-meshheading:55045-Adolescent,
pubmed-meshheading:55045-Adult,
pubmed-meshheading:55045-Aged,
pubmed-meshheading:55045-Alopecia Areata,
pubmed-meshheading:55045-Female,
pubmed-meshheading:55045-Humans,
pubmed-meshheading:55045-Injections, Intravenous,
pubmed-meshheading:55045-Male,
pubmed-meshheading:55045-Middle Aged,
pubmed-meshheading:55045-Prednisolone,
pubmed-meshheading:55045-Time Factors
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
Large doses of glucocorticoid in the treatment of alopecia areata.
|
| pubmed:publicationType |
Journal Article
|