| pubmed-article:5501259 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:5501259 | lifeskim:mentions | umls-concept:C0734999 | lld:lifeskim |
| pubmed-article:5501259 | lifeskim:mentions | umls-concept:C0234388 | lld:lifeskim |
| pubmed-article:5501259 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:5501259 | pubmed:dateCreated | 1971-4-6 | lld:pubmed |
| pubmed-article:5501259 | pubmed:abstractText | 1. Intracellular recording of the transmembrane potential in mouse pancreatic cells revealed a membrane potential of -20.1 +/- 0.8 mV for islet cells and -41.2 +/- 1.4 mV for acinar cells.2. The membrane potential of islet cells was glucose dependent and in the absence of glucose the cells hyperpolarized to -32.7 mV; with glucose 27.7 mM they depolarized to -16.1 mV.3. Above a threshold concentration of glucose (4 mM) small action potentials of amplitude 1-4 mV were induced in islet cells. The percentage of cells impaled exhibiting action potentials reached a maximum of 80% at 27.7 mM glucose.4. Mannose 16.6 mM was similar to glucose in its ability to induce action potential discharge in islet cells.5. 2,4-Dinitrophenol (0.25 mM) hyperpolarized islet cells and blocked electrical activity induced by glucose 11.1 mM.6. Adrenaline (1 muM) completely blocked glucose-induced electrical activity but without altering the membrane potential.7. The origin and functional significance of glucose-induced electrical activity in islet cells is discussed in relation to insulin secretion. | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:language | eng | lld:pubmed |
| pubmed-article:5501259 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:5501259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5501259 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:5501259 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:5501259 | pubmed:issn | 0022-3751 | lld:pubmed |
| pubmed-article:5501259 | pubmed:author | pubmed-author:DeanP MPM | lld:pubmed |
| pubmed-article:5501259 | pubmed:author | pubmed-author:MatthewsE KEK | lld:pubmed |
| pubmed-article:5501259 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:5501259 | pubmed:volume | 210 | lld:pubmed |
| pubmed-article:5501259 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:5501259 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:5501259 | pubmed:pagination | 255-64 | lld:pubmed |
| pubmed-article:5501259 | pubmed:dateRevised | 2010-9-10 | lld:pubmed |
| pubmed-article:5501259 | pubmed:meshHeading | pubmed-meshheading:5501259-... | lld:pubmed |
| pubmed-article:5501259 | pubmed:meshHeading | pubmed-meshheading:5501259-... | lld:pubmed |
| pubmed-article:5501259 | pubmed:meshHeading | pubmed-meshheading:5501259-... | lld:pubmed |
| pubmed-article:5501259 | pubmed:year | 1970 | lld:pubmed |
| pubmed-article:5501259 | pubmed:articleTitle | Glucose-induced electrical activity in pancreatic islet cells. | lld:pubmed |
| pubmed-article:5501259 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:5501259 | lld:pubmed |
