Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-4-2
pubmed:abstractText
Techniques for the amino acid sequence analysis of subnanomole quantities of polypeptides have been applied to characterize beta2-microglobulin and transplantation antigens of the mouse isolated from spleen cells by indirect immunoprecipitation. Eleven residues were identified throughout the NH2-terminal 27 residues of the beta2-microglobulin; all were identical to residues seen at the corresponding positions of beta2-microglobulins from other species. Two K and two D transplantation antigens were examined and the following generalizations emerged from the limited partial amino-acid sequence data: (1) the K and D molecules are homologous to one another; (2) they do not show amino acid sequence homology with immunoglobulins; (3) the two K and two D molecules differ from one another by multiple amino acid substitutions; and (4) the K molecules as a class cannot be distinguished from the D molecules as a class. The genetic and evolutionary implications of these observations are discussed.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-1055432, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-1059107, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-1089744, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-1134585, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-1163764, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-1172603, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4098765, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4106303, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4108876, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4113158, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4124595, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4134154, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4134396, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4139785, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4185453, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4507614, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4525163, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4586824, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4598853, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4613264, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-46243, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-46618, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-47219, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-48298, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4833516, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4841060, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-4850708, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-53836, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-5461774, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-813219, http://linkedlifedata.com/resource/pubmed/commentcorrection/54922-813561
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
599-603
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Structure and evolution of transplantation antigens: partial amino-acid sequences of H-2K and H-2D alloantigens.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.