rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1971-1-23
|
pubmed:abstractText |
1. Isolated left-atrial strips of guinea-pigs were driven electrically at a constant rate and log-concentration curves were determined for the positive inotropic effect of noradrenaline and tyramine.2. The atrial tissue from endotoxin-treated animals had a reduced sensitivity to noradrenaline and tyramine.3. After endotoxin, the sensitizing effect of cocaine on the response to noradrenaline was normal but accumulation of (3)H-noradrenaline in nerve terminals was markedly reduced.4. Atrial tissue of endotoxin-treated guinea-pigs responded normally to stretch.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0007-1188
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
688-95
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:5485145-Animals,
pubmed-meshheading:5485145-Cocaine,
pubmed-meshheading:5485145-Drug Synergism,
pubmed-meshheading:5485145-Elasticity,
pubmed-meshheading:5485145-Guinea Pigs,
pubmed-meshheading:5485145-Heart,
pubmed-meshheading:5485145-Heart Atria,
pubmed-meshheading:5485145-Male,
pubmed-meshheading:5485145-Myocardium,
pubmed-meshheading:5485145-Norepinephrine,
pubmed-meshheading:5485145-Shock, Septic,
pubmed-meshheading:5485145-Tritium,
pubmed-meshheading:5485145-Tyramine
|
pubmed:year |
1970
|
pubmed:articleTitle |
Noradrenaline and tyramine action on isolated atrial muscle of endotoxin-treated guinea-pigs.
|
pubmed:publicationType |
Journal Article,
In Vitro
|