Linked Life Data

547321

Source:http://linkedlifedata.com/resource/pubmed/id/547321

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-8-25
pubmed:abstractText
Inflammatory lesions of the duodenal mucosa and duodenal ulcers can be produced in animal experiments by pantothenic acid deficiency. We investigated this model in 30 rats of both sexes aged 2 or 6 months and 1 year. During 3 months the experimental animals were feeded with a diet including all the known nutritional factors except pantothenic acid, while the control animals received a standard diet. Thereafter paraffin and semithin sections of the duodenum showed mucosal changes and lesions (so-called Leistenspitzenerosionen, submucosal oedemas, initial duodenitis) in about three fourths of the experimental animals.--Yet there were no ulcers.--They, however, can be demonstrated when lengthening the experimental period as shown by our investigations using male rats aged 1 year (time for producing ulcers: approximate 5 months).--The duodenal lesions are typical and regularly to be reproduced. In this context their role as a precursor to an ulcer is discussed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0300-9130
pubmed:author
pubmed:issnType
Print
pubmed:volume
176
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-16
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
[Duodenal lesions produced by pantothenic acid deficiency in animal experiments (author's transl)].
pubmed:publicationType
Journal Article, English Abstract