Linked Life Data

5445047

Source:http://linkedlifedata.com/resource/pubmed/id/5445047

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1970-7-2
pubmed:abstractText
Experiments were carried out to evaluate the adequacy of internal carotid perfusion of the isolated canine brain and the application of a perfusion apparatus which was designed to facilitate environmental control for the isolated functioning organ. Anatomic considerations and the surgical isolation of the cerebral vasculature are presented in detail. Intact animals were used to provide physiologic arterial blood which was pumped under pressure control to six brains which were maintained at simulated low, normal and high intracranial pressures. Good electrocortical activity has been preserved for up to eight hours in the preparation.The methods provide a useful model for the future investigation of cerebral circulation, metabolism and function under normal and various pathophysiologic conditions.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0008-4409
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
102
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
839-42
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1970
pubmed:articleTitle
Isolation and controlled perfusion of the canine brain.
pubmed:publicationType
Journal Article