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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1970-8-11
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Africa,
http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara,
http://linkedlifedata.com/resource/pubmed/keyword/Anovulation,
http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Eastern Africa,
http://linkedlifedata.com/resource/pubmed/keyword/English Speaking Africa,
http://linkedlifedata.com/resource/pubmed/keyword/Examinations And Diagnoses,
http://linkedlifedata.com/resource/pubmed/keyword/Infertility,
http://linkedlifedata.com/resource/pubmed/keyword/Kenya,
http://linkedlifedata.com/resource/pubmed/keyword/Menstruation Disorders,
http://linkedlifedata.com/resource/pubmed/keyword/Prospective Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Reproduction,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Treatment
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0012-835X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
212-6
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pubmed:dateRevised |
2004-11-17
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pubmed:otherAbstract |
PIP: A prospective study of 200 patients complaining of infertility was conducted to determine the incidence of detectable lesions, in particular tubal occlusion, pelvic tuberculosis, and anovulation. These cases of primary and secondary infertility presented at the Gynecological Outpatient Department of the Kenyatta National Hospital in Nairobi. Tubal insufflation and endometrial biopsy were performed as outpatient procedures without general anesthesia. The 200 patients were divided into those with primary infertility who had never conceived, and those with secondary infertility who had conceived on at least 1 occasion. The Mantoux test was positive in 93 patients (46.5%) and negative in 107 (53.5%). The 4 cases of tuberculous endometritis diagnosed in the study had strongly positive results, but the Mantoux result bore no significant relationship to the incidence of tubal occlusion. Culture of the endometrium for M. tuberculosis in 200 cases yeilded 3 positive cultures (1.5%). These corresponded to the histological results and a definite diagnosis of tuberculosis endometritis was therefore established in 3 cases. In the 4th case, where the culture was negative, the histological evidence was very convincing, and it was considered justified to commence antituberculous therapy on this evidence alone. Tubal insufflation was performed in 3 out of these 4 cases and all showed blocked tubes. The menstrual cycles of 26 cases out of the 30 found to have proliferative phase endometrium were regular and unremarkable. The remaining 4 patients, where the histological pattern showed evidence of prolonged estrogen stimulation, had irregular menses suggestive of anovulatory menstruation. Of the 200 cases investigated, 98 patients (49%) had a demonstrable lesion preventing conception, 96 having blocked tubes, 1 having tuberculosis endometritis alone, and 1 having anovulation alone. 6 cases had 2 lesions preventing conception. No patients in the study became pregnant during the course of the investigation.
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pubmed:meshHeading |
pubmed-meshheading:5424987-Adnexal Diseases,
pubmed-meshheading:5424987-Fallopian Tubes,
pubmed-meshheading:5424987-Female,
pubmed-meshheading:5424987-Humans,
pubmed-meshheading:5424987-Infertility, Female,
pubmed-meshheading:5424987-Kenya,
pubmed-meshheading:5424987-Prospective Studies,
pubmed-meshheading:5424987-Tuberculosis, Female Genital
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pubmed:year |
1970
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pubmed:articleTitle |
The investigation and management of infertility in East Africa. A prospective study of 200 cases.
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pubmed:publicationType |
Journal Article
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