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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5689
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pubmed:dateCreated |
1970-3-26
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pubmed:abstractText |
The effect of ergotamine and ergometrine on the venous compliance of the forearm has been studied in normal persons. Ergotamine tartrate (0.25 mg. intravenously) led to a fall in venous compliance amounting to 49% on average, while ergometrine maleate (0.25 mg. intravenously) caused a reduction of 41%; these changes were statistically significant. The potent veno-constrictor action of these ergot alkaloids appears to be a major component of the circulatory response to small doses and may be important in provoking the harmfull cardiovascular side-effects (such as angina and pulmonary oedema) that are sometimes observed in patients with pre-existing heart disease.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-1447
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-42
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pubmed:dateRevised |
2010-10-26
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pubmed:meshHeading |
pubmed-meshheading:5413950-Angina Pectoris,
pubmed-meshheading:5413950-Blood Pressure,
pubmed-meshheading:5413950-Elasticity,
pubmed-meshheading:5413950-Ergonovine,
pubmed-meshheading:5413950-Ergotamine,
pubmed-meshheading:5413950-Forearm,
pubmed-meshheading:5413950-Humans,
pubmed-meshheading:5413950-Plethysmography,
pubmed-meshheading:5413950-Pulmonary Edema,
pubmed-meshheading:5413950-Regional Blood Flow,
pubmed-meshheading:5413950-Veins
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pubmed:year |
1970
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pubmed:articleTitle |
Effect of ergotamine and ergometrine on forearm venous compliance in man.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
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