Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1980-6-25
pubmed:abstractText
1. Recordings have been obtained from single sympathetic fibres to the left kidney in anaesthetized adult spontaneously hypertensive (SH) rats and Wistar-Kyoto normotensive (WK) rats. 2. Under control conditions SH rats had a mean sympathetic activity of 3.3 +/- SE 0.45 Hz and WK rats 1.6 +/- 0.23 Hz. During noradrenaline infusion single fibre discharge decreased gradually to low levels in both SH and WK rats. The absolute decrease in fibre activity/mmHg rise of arterial pressure was greater in SH rats than in WK rats, but the reverse was true when the discharge reduction was expressed as a percentage change. 3. Recordings have also been obtained from the left splanchnic nerve in awake SH and WK rats. Upon volume load with blood, in SH rats the sympathetic activity decreased significantly more than in WK rats. 4. Thus the sympathetic discharge to the kidneys is higher in SH rats than in WK rats. Upon volume load SH rats show an exaggerated reflex response, probably due to an augmented volume-receptor response.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0143-5221
pubmed:author
pubmed:issnType
Print
pubmed:volume
57 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197s-199s
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Recordings of renal and splanchnic sympathetic nervous activity in normotensive and spontaneously hypertensive rats.
pubmed:publicationType
Journal Article, Comparative Study