Linked Life Data

536694

Source:http://linkedlifedata.com/resource/pubmed/id/536694

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1980-5-14
pubmed:abstractText
Clusters of inside cells (ICs) were isolated immunosurgically from morulae and early cavitating blastocysts, and cultured for varying periods in vitro. The ICs responded to their changed position by transformation to a blastocyst-like vesicle and also showed a correlated synthesis of trophectodermal-marker polypeptides. Both changes were inhibited by alpha-amanitin, indicating that transcriptional events are involved in this response to changed position. Inner cell masses (ICMs), isolated immunosurgically from expanded blastocysts, did not undergo a morphological transformation to a blastocyst-like structure and did not show a corresponding and complete change in synthesis of trophectodermal-marker polypeptides. Elements of the change in polypeptide activity were, however, present, suggesting an ineffective response to position by the ICMs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-0752
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
335-44
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Molecular differentiation of inside cells and inner cell masses isolated from the preimplantation mouse embryo.
pubmed:publicationType
Journal Article