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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1980-5-14
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pubmed:abstractText |
The effector cell populations in human peripheral blood responsible for antibody-dependent cellular cytotoxicity against allogenic cells coated with HLA polyspecific antibodies were investigated using several separation techniques including preparative electrophoresis. Electrophoresis produced a marked effector cells enrichment in a range of 2--5 fractions which exhibited an intermediary electrophoretic mobility. Monocytic cells do not contribute an effector mechanism but minor subsets of polymorphonuclear cells and nylon wool non-adherent non-phagocytic lymphocytes displayed ADCC. Both effector cell populations were found to exhibit a similar electrical charge of cell surface centered around -1.05 micrometer . sec-1 V-1 cm. These observations provided a precise biophysical basis for the identification of effector cells in ADCC.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-1000082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-10605452,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-1083299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-1084361,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-1086232,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-128570,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-140193,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-197171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-299919,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-301299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-301451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-301453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-301469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-302753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-304041,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-304874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-307407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-312167,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-325129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-325136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-329907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-330057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-4275547,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-4280162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-4544817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-4549628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-4587740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-4589574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-52217,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-591000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-638013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-830749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-919024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/535187-968932
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0009-9104
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
549-60
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:535187-Adult,
pubmed-meshheading:535187-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:535187-Cell Separation,
pubmed-meshheading:535187-Electrophoresis,
pubmed-meshheading:535187-Esterases,
pubmed-meshheading:535187-Humans,
pubmed-meshheading:535187-Killer Cells, Natural,
pubmed-meshheading:535187-Membrane Potentials,
pubmed-meshheading:535187-Monocytes,
pubmed-meshheading:535187-Neutrophils
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pubmed:year |
1979
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pubmed:articleTitle |
Characterization of the human peripheral effector cells mediating antibody dependent cellular cytotoxicity against allogenic cells.
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pubmed:publicationType |
Journal Article,
Comparative Study
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