rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1969-12-18
|
pubmed:abstractText |
1. The release of prostaglandin E(1) from the rat phrenic nerve-diaphragm preparation during tetanic contraction of the muscle in response to nerve stimulation is reported. Tentative identification of the prostaglandin depended on solvent extraction column and thin-layer chromatography and parallel biological assay.2. Polar lipid substances were released from the preparation in the absence of nerve stimulation by (+)-tubocurarine and noradrenaline.3. The output on nerve stimulation was not abolished by (+)-tubocurarine, hemicholinium, bretylium or phenoxybenzamine added to the bath.4. The possible origin of these prostaglandins is discussed.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0007-1188
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
37
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
698-704
|
pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:5348472-Animals,
pubmed-meshheading:5348472-Biological Assay,
pubmed-meshheading:5348472-Bretylium Compounds,
pubmed-meshheading:5348472-Chromatography, Thin Layer,
pubmed-meshheading:5348472-Diaphragm,
pubmed-meshheading:5348472-Electric Stimulation,
pubmed-meshheading:5348472-Female,
pubmed-meshheading:5348472-Hemicholinium 3,
pubmed-meshheading:5348472-Male,
pubmed-meshheading:5348472-Norepinephrine,
pubmed-meshheading:5348472-Phenoxybenzamine,
pubmed-meshheading:5348472-Phrenic Nerve,
pubmed-meshheading:5348472-Prostaglandins,
pubmed-meshheading:5348472-Rats,
pubmed-meshheading:5348472-Tubocurarine
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pubmed:year |
1969
|
pubmed:articleTitle |
The release of prostaglandin E1 from the rat phrenic nerve-diaphragm preparation.
|
pubmed:publicationType |
Journal Article,
In Vitro
|