Linked Life Data

5273896

Source:http://linkedlifedata.com/resource/pubmed/id/5273896

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1971-1-13
pubmed:abstractText
A simple model for steady-state transport of a neutral molecule across a membrane is investigated in a preliminary way. In this model, there is a possible conformation change in each membrane unit which alters the access of the binding site for the transported molecule from one bath to the other. Thus, transport cannot be accomplished without a conformation change. Furthermore, we assume a cooperative interaction between nearest-neighbor membrane units in the same conformation. Then, with suitable rate constants and bath concentrations, and if the interaction energy is large enough, the membrane will oscillate back and forth between the two conformational phases, producing a surge of flux in each cycle. The period of the cycle depends on the times necessary to nucleate the two phase transitions.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-96
pubmed:dateRevised
2010-9-10
pubmed:meshHeading
pubmed:year
1970
pubmed:articleTitle
Cooperative effects in models of steady-state transport across membranes. II. Oscillating phase transition.
pubmed:publicationType
Journal Article