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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1970-10-6
|
| pubmed:abstractText |
The preparation and properties of three geometric isomers of 13-desmethyl retinal (13-dmr) are described. They are analogous to the all-trans, 11-cis, and 9-cis isomers of retinal since two of the cis isomers combine with cattle opsin to form pigments which are spectrally indistinguishable from rhodopsin and isorhodopsin and the all-trans isomer is unreactive.The pigment which resembles rhodopsin, 13-desmethyl (13-dm) rhodopsin, is formed at about one ninth the rate at which 11-cis retinal reacts with opsin at 20 degrees C. The reaction with 13-dmr does not go to completion; and 0.05 M hydroxylamine, to which rhodopsin is stable, decomposes 13-dm rhodopsin. Irradiation of 13-dm rhodopsin results in a cis --> trans isomerization of the chromophore; but the photosensitivity of 13-dm rhodopsin is only 40 per cent that of rhodopsin.13-dm isorhodopsin, the 13-desmethyl analogue of isorhodopsin, is formed at approximately the same specific rate as 13-dm rhodopsin. The reaction goes to completion and the pigment is not decomposed by 0.03 M hydroxylamine. 13-dm isorhodopsin can also be photolyzed to the all-trans chromophore plus opsin.
|
| pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-13011282,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-13297008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-14002749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-14080814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-14282987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-14367777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-16590155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-16748320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-5608595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-5659644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-5811778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/5271178-5926366
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0027-8424
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
66
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
531-8
|
| pubmed:dateRevised |
2009-11-18
|
| pubmed:meshHeading | |
| pubmed:year |
1970
|
| pubmed:articleTitle |
13-desmethyl rhodopsin and 13-desmethyl isorhodopsin: visual pigment analogues.
|
| pubmed:publicationType |
Journal Article
|