Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1980-3-24
pubmed:abstractText
Little (lit) is a single gene dwarf mutation described in the C57Bl/6J strain of laboratory mouse. This study was designed to determine the effect of the mutation little on mammary gland development during pregnancy and post-partum periods. Failure of mutant females to lactate at first parturition appears to be due to the endocrine environment of the gland rather than any intrinsic defect of the mammary epithelium. Treatment of primiparous lit/lit females with exogenous growth hormone or prolactin resulted in lactogenesis. Treatment with hydrocortisone resulted in increased amounts of organized rough endoplasmic reticulum but lactation did not occur.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0040-8166
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
773-80
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Mammary gland development during pregnancy in the dwarf mouse mutant, little.
pubmed:publicationType
Journal Article