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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1980-2-28
|
| pubmed:abstractText |
Cyproterone acetate, an antiandrogen drug, is used to reduce mammalian fertility. Effects on the human testis are controversial. Findings in this study reveal that long-term treatment-7 months with 200 mg/day-leads to disappearance of the germinal cells and to Sertoli cells with either a normal or undifferentiated aspect as well as involution of the Leydig cell. Some pathogenetic hypotheses on the action of cyproterone acetate upon human spermatogenesis are discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0148-5016
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
263-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:518209-Cyproterone,
pubmed-meshheading:518209-Humans,
pubmed-meshheading:518209-Leydig Cells,
pubmed-meshheading:518209-Male,
pubmed-meshheading:518209-Middle Aged,
pubmed-meshheading:518209-Prostatic Neoplasms,
pubmed-meshheading:518209-Sertoli Cells,
pubmed-meshheading:518209-Testis
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Histological characteristics of the human testis after long-term treatment with cyproterone acetate.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|