Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1972-3-22
pubmed:abstractText
Charcot-Leyden crystals develop spontaneously in certain diseases of man and can be formed within minutes from eosinophils lysed with a surface-active agent (Aerosol-OT). Treated human eosinophils examined by electron microscopy showed the general features of cell lysis. After disruption of the eosinophilic granule of man, there remained an insoluble crystalline core, which was now more dispersed, a few tubular structures resembling microtubules and a fine granular accumulation around the periphery of the granule. It is suggested that such dispersion represents rearrangement of the crystalline structure allowing the material of the core to be incorporated into a Charcot-Leyden crystal. In guinea pig eosinophils, Charcot-Leyden crystals were not found even after prolonged lysis. By electron microscopy, the cellular changes in guinea pig eosinophils were generally similar to, but developed more slowly than, those in human eosinophils. Tubular structures detected in the cortical region of the granule were more numerous than thosenoted in the disrupted eosinophil granule of man. The different reaction to injury of the eosinophils of man and those of the guinea pig appears to be characteristic for each of the two species.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13068370, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13376051, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13509005, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13604850, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13731423, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13843925, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13868559, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13894888, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-13970020, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-14074391, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-14212120, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-14222819, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-14325469, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-14448981, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-4161776, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-4181945, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-4873274, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-5224582, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-5320628, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-5459000, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-5487205, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-5922745, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-5929546, http://linkedlifedata.com/resource/pubmed/commentcorrection/5134886-6050946
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0002-9440
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
311-24
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
Charcot-Leyden crystals. Formation from primate and lack of formation from nonprimate eosinophils.
pubmed:publicationType
Journal Article