Linked Life Data

511128

Source:http://linkedlifedata.com/resource/pubmed/id/511128

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1980-2-15
pubmed:abstractText
Epidemiologic differences that appear to be geographic or climatic actually relate more closely to socioeconomics and sanitation. Regardless of etiology, the major management problems are those of dehydration and its sequelae. Progress toward development of antibacterial and antiviral vaccines is discussed. Next month the viral and bacterial agents that cause diarrheal infections will be reviewed.
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0018-5809
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-100
pubmed:dateRevised
2009-11-11
pubmed:otherAbstract
PIP: Diarrheal disease is bacterial in much of the Third World and viral elsewhere. In the poorest underdeveloped country, as many as 15% of children die from diarrheal disease before their third birthday. This association with geographical or climatic areas of the world, however, is actually a reflection of low socioeconomic levels and poor sanitation for practically all of diarrhea's infectious agents are in fact ubiquitous worldwide. Clinical problems associated with acute diarrhea, irrespective of etiology, relate to dehydration that results from abnormal loss of water and electrolytes in stools. Because an infant's total body weight is 70% water (as opposed to 60% in adults), diarrhea is a particular threat. During diarrheal disease, the major event is the disruption of the recycling of electrolyte-rich digestive fluids, which are nomally secreted into the gastrointestinal tract and then 99% reabsorbed. Treatments include preventive methods, such as public health improvements, and rehydration with glucose-water solutions, either orally or intravenously, depending on extent of dehydration. Vaccine development against rotavirus infection has been stymied by inability to cultivate the organism. However, immunoprophylaxis of bacterial diarrheas has made progress in developing vaccines against enterotoxigenic Escherichia coli. The role of immunity transmitted by breastfeeding is also emphasized.
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Acute diarrheal infections in infants. I. Epidemiology, Treatment, and prospects for immunoprophylaxis.
pubmed:publicationType
Journal Article