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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1975-11-26
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pubmed:abstractText |
A particle fraction with a density of 1.15-1.19 g/cm3 was isolated from the cytoplasm of a human cell line established in culture from the bone marrow of an untreated patient with polycythemia vera. Electron micrographs of cross sections of cells and cell homogenates revealed virus-like particles on which DNA could be synthesized. An RNA-dependent DNA polymerase, isolated from the particles, preferred poly(rA)-oligo(dT) over poly(dA)-oligo(dT) and was able to polymerize deoxyguanosine monophosphate in a reaction stimulated by poly(rC)-oligo(dG).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0027-8874
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
537-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:51088-Bone Marrow,
pubmed-meshheading:51088-Cell Line,
pubmed-meshheading:51088-Cytoplasm,
pubmed-meshheading:51088-Guanine Nucleotides,
pubmed-meshheading:51088-Humans,
pubmed-meshheading:51088-Oligodeoxyribonucleotides,
pubmed-meshheading:51088-Oncogenic Viruses,
pubmed-meshheading:51088-Poly A,
pubmed-meshheading:51088-Poly C,
pubmed-meshheading:51088-Poly G,
pubmed-meshheading:51088-Polycythemia Vera,
pubmed-meshheading:51088-RNA, Viral,
pubmed-meshheading:51088-RNA-Directed DNA Polymerase,
pubmed-meshheading:51088-Templates, Genetic,
pubmed-meshheading:51088-Thymine Nucleotides
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pubmed:year |
1975
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pubmed:articleTitle |
Particle-associated RNA dependent DNA polymerase and high-molecular-weight RNA in a human cell line derived from polycythemia vera bone marrow.
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pubmed:publicationType |
Journal Article
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