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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1980-2-26
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pubmed:abstractText |
The Merkel cells from sinus hair follicles of rats were investigated by immunohistochemistry using different antisera against neuropeptides and gastroenteropancreatic (GEP)-hormones. For the first time it has been demonstrated that Merkel cells exhibit an immunoreactivity towards metenkephalin (methionine-enkephalin). The met-enkephalin immunoreactivity was restricted to Merkel cells and was not found in associated nerve axons or terminals. Denervation of Merkel cells did not affect the met-enkephalin immunoreactivity. Antisera leu-enkephalin (leucine-enkephalin) and other polypeptides did not produce an immunoreaction. The demonstration of met-enkephalin-like immunoreactivity supports the concept that the Merkel cell is a member of the paraneuronal system and a potential neuroreceptor cell.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0302-766X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
201
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:509486-Animals,
pubmed-meshheading:509486-Axons,
pubmed-meshheading:509486-Endorphins,
pubmed-meshheading:509486-Enkephalins,
pubmed-meshheading:509486-Female,
pubmed-meshheading:509486-Immunochemistry,
pubmed-meshheading:509486-Male,
pubmed-meshheading:509486-Melanocytes,
pubmed-meshheading:509486-Rats,
pubmed-meshheading:509486-Sensory Receptor Cells
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pubmed:year |
1979
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pubmed:articleTitle |
Met enkephalin-like immunoreactivity in Merkel cells.
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pubmed:publicationType |
Journal Article
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