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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
6
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|
pubmed:dateCreated |
1980-2-26
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|
pubmed:abstractText |
It was shown that 1-phenylethylbiguanide (phenformin) administered orally to mice at a dose of 2 mg/day potentiated the antitumor effect of cyclophosphamide on transplantable squamous cell cervical carcinoma, hepatoma-22a and Lewis lung tumor, but did not alter the effect of cyclophosphamide on sarcoma-180 and L-1210. Oral administration of phenformin (5 mg/day) to rats with transplanted Walker 256 carcinoma enhanced the antitumor effect of hydrazine sulfate.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0304-3835
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-61
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:509414-Animals,
pubmed-meshheading:509414-Carcinoma 256, Walker,
pubmed-meshheading:509414-Cyclophosphamide,
pubmed-meshheading:509414-Drug Synergism,
pubmed-meshheading:509414-Drug Therapy, Combination,
pubmed-meshheading:509414-Female,
pubmed-meshheading:509414-Hydrazines,
pubmed-meshheading:509414-Liver Neoplasms, Experimental,
pubmed-meshheading:509414-Lung Neoplasms,
pubmed-meshheading:509414-Mice,
pubmed-meshheading:509414-Mice, Inbred Strains,
pubmed-meshheading:509414-Neoplasms, Experimental,
pubmed-meshheading:509414-Phenformin,
pubmed-meshheading:509414-Sarcoma 180,
pubmed-meshheading:509414-Uterine Cervical Neoplasms
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pubmed:year |
1979
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pubmed:articleTitle |
Potentiation of antitumor effect of cyclophosphamide and hydrazine sulfate by treatment with the antidiabetic agent, 1-phenylethylbiguanide (phenformin).
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pubmed:publicationType |
Journal Article
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