|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1980-1-28
|
|
pubmed:abstractText |
Estradiol metabolism in 10 patients with systemic lupus erythematosus (SLE) and 29 normal controls was studied by measurement of urinary metabolites after injection of labeled 3H-estradiol. Patients with SLE manifested increased 16-hydroxylation of estrone. Diseases men differed from diseases women to the extent that only 16 alpha-hydroxyestrone was elevated in men, whereas women had elevations of both 16 alpha-hydroxyestrone and estriol. These data suggest that patients with SLE have abnormal patterns of estradiol metabolism, leading to increased estrogenic activity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
22
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1195-8
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:508372-Adolescent,
pubmed-meshheading:508372-Adult,
pubmed-meshheading:508372-Estradiol,
pubmed-meshheading:508372-Estriol,
pubmed-meshheading:508372-Estrogens,
pubmed-meshheading:508372-Estrone,
pubmed-meshheading:508372-Female,
pubmed-meshheading:508372-Humans,
pubmed-meshheading:508372-Hydroxyestrones,
pubmed-meshheading:508372-Lupus Erythematosus, Systemic,
pubmed-meshheading:508372-Male,
pubmed-meshheading:508372-Middle Aged
|
|
pubmed:year |
1979
|
|
pubmed:articleTitle |
Alterations of estrogen metabolism in systemic lupus erythematosus.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
