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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1980-1-28
|
| pubmed:abstractText |
A structure ocular toxicity study in the rat of (4' - pyridyl) - 1 piperazine and of some derivatives with psychopharmacological profile, allows some interesting conclusions. (4' - pyridyl) - 1 piperazine does not lead to crystalline lens opacity, though some aryloxypropanol or aryloxypropyl derivatives do. At least, (2' - pyridyl) - 1 piperazine and one aryloxpropanol derivative do not improve cataract. So the appearance of cataracts is probably due to substitution of an alkylaryl side chain on the N-4 position of (4' - pyridyl) - piperazine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0249-6402
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
99-102
|
| pubmed:dateRevised |
2008-2-26
|
| pubmed:meshHeading |
pubmed-meshheading:505449-Animals,
pubmed-meshheading:505449-Behavior, Animal,
pubmed-meshheading:505449-Body Weight,
pubmed-meshheading:505449-Cataract,
pubmed-meshheading:505449-Lens, Crystalline,
pubmed-meshheading:505449-Male,
pubmed-meshheading:505449-Piperazines,
pubmed-meshheading:505449-Rats,
pubmed-meshheading:505449-Skin,
pubmed-meshheading:505449-Structure-Activity Relationship
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Induction of cataracts in the rat by derivatives of (4' -pyridyl) - 1 piperazine.
|
| pubmed:publicationType |
Journal Article
|