| pubmed-article:5024037 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:5024037 | lifeskim:mentions | umls-concept:C0023374 | lld:lifeskim |
| pubmed-article:5024037 | lifeskim:mentions | umls-concept:C2257191 | lld:lifeskim |
| pubmed-article:5024037 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:5024037 | pubmed:dateCreated | 1972-7-12 | lld:pubmed |
| pubmed-article:5024037 | pubmed:abstractText | Inosinic acid dehydrogenase was evaluated in normal subjects and in patients with the Lesch-Nyhan syndrome. A significant difference in activity was found between erythrocytes derived from normal controls (1.21+/-0.47 pmoles/hr per mg protein) and from 15 patients with the Lesch-Nyhan syndrome (6.72+/-6.23 pmoles/hr per mg protein). However, no difference in activity was demonstrable in muscle or leukocytes derived from normal and Lesch-Nyhan patients. The increased activity of inosinic acid dehydrogenase in erythrocytes from patients with the Lesch-Nyhan syndrome is due to stabilization of the enzyme in vivo as well as the absence of an inhibitor which is present in erythrocytes from normal subjects. | lld:pubmed |
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| pubmed-article:5024037 | pubmed:language | eng | lld:pubmed |
| pubmed-article:5024037 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5024037 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:5024037 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:5024037 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:5024037 | pubmed:issn | 0021-9738 | lld:pubmed |
| pubmed-article:5024037 | pubmed:author | pubmed-author:KelleyW NWN | lld:pubmed |
| pubmed-article:5024037 | pubmed:author | pubmed-author:HolmesE WEW | lld:pubmed |
| pubmed-article:5024037 | pubmed:author | pubmed-author:McDonaldJ AJA | lld:pubmed |
| pubmed-article:5024037 | pubmed:author | pubmed-author:PehlkeD MDM | lld:pubmed |
| pubmed-article:5024037 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:5024037 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:5024037 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:5024037 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:5024037 | pubmed:pagination | 1398-404 | lld:pubmed |
| pubmed-article:5024037 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:5024037 | pubmed:year | 1972 | lld:pubmed |
| pubmed-article:5024037 | pubmed:articleTitle | Inosinic acid dehydrogenase activity in the Lesch-Nyhan syndrome. | lld:pubmed |
| pubmed-article:5024037 | pubmed:publicationType | Journal Article | lld:pubmed |
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