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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1980-1-28
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pubmed:abstractText |
Rat cell lines tranformed by viral DNA fragments, EcoRI-C and HindIII-G, of adenovirus type 12 DNA were analyzed for the viral transforming DNA sequences present in cell DNAs. Cell lines transformed by the EcoRI-C fragment of adenovirus type 12 DNA (leftmost 16.5% of the viral genome) contain most of the HindIII-G sequences of the HindIII-G fragment, but at a different frequency depending on the portions of the fragment. The sequence of the AccI-H fragment of adenovirus type 12 DNA (the left part of the HindIII-G; leftmost 4.5% of the viral genome) was detected dominantly in cells transformed by the HindIII-G fragment Southern blot analysis showed that viral DNA sequences are present at multiple integration sites in high-molecular-weight cell DNA from cells transformed by the EcoRI-C or HindIII-G fragment of adenovirus type 12 DNA. These results suggest that most of the HindIII-G sequences in cells transformed by the HindIII-G fragment are present as fragmented forms.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-1057486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-1113376,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-13950097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-14166590,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-14212121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-14215651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-334244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-4127968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-4320675,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-442537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-452415,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-467887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-4904090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-5227675,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-608591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-676073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-863170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-881736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-898675,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-919348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-919350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-947550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/501799-988194
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
379-85
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:501799-Adenoviruses, Human,
pubmed-meshheading:501799-Animals,
pubmed-meshheading:501799-Base Sequence,
pubmed-meshheading:501799-Cell Line,
pubmed-meshheading:501799-Cell Transformation, Viral,
pubmed-meshheading:501799-DNA,
pubmed-meshheading:501799-DNA, Viral,
pubmed-meshheading:501799-DNA Restriction Enzymes,
pubmed-meshheading:501799-Genes, Viral,
pubmed-meshheading:501799-Humans,
pubmed-meshheading:501799-Nucleic Acid Hybridization,
pubmed-meshheading:501799-Rats
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pubmed:year |
1979
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pubmed:articleTitle |
Transforming DNA sequences in rat cells transformed by DNA fragments of highly oncogenic human adenovirus type 12.
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pubmed:publicationType |
Journal Article
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