Linked Life Data

498038

Source:http://linkedlifedata.com/resource/pubmed/id/498038

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1980-1-24
pubmed:abstractText
In previous studies we showed that spontaneous bacterial adherence can be used to identify human lymphocyte subpopulations and to demonstrate variable binding patterns in chronic lymphocytic leukemia (CLL). In this study, 10 strains of bacteria of different genera and species were used in blood smears from 24 CLL patients to determine the percentages of lymphocytes that bind bacteria. From these percentages, binding indices were calculated. The symptoms and other laboratory tests were independently recorded and the stages determined. When the two sets of data were compared, relatively low binding indices were found in symptomatic patients or in Stages III and IV; relatively high binding indices were found in asymptomatic patients or in Stages I and II. We suggest that with progression of leukemia, lymphocytes with less "lectin" recognition potential are selected and escape any control mechanism of proliferation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1665-70
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Relationship between bacterial binding to lymphocytes and clinical features in chronic lymphocytic leukemia.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.