Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
815
pubmed:dateCreated
1969-5-2
pubmed:abstractText
The immunological properties of the erythrocyte catalase of mice-normal (wild type) strain, one lacking catalase (acatalasemic), and four with only slight catalase activity (hypocatalasemic strains)-have been investigated. Agardiffusion tests and antigen titration of red-cell lysates against rabbit antiserum to catalase from normal mouse blood showed that immunologically identical catalase protein was present in large amounts in the acatalasemic as well as in the hypocatalasemic mutant strains. Despite lack of catalatic activity, the erythrocytes lacking catalase as well as those with only a little catalase contain catalase protein that has been modified at the site of enzyme activity, although the antigenic determinants are identical with those of normal catalase protein. This mutation is purely structural, being characterized by modification of the enzyme active site but not of the antigenic site.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
159
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
638-40
pubmed:dateRevised
2007-8-17
pubmed:meshHeading
pubmed:year
1968
pubmed:articleTitle
Blood catalsase polymorphism: some immunological aspects.
pubmed:publicationType
Journal Article