Linked Life Data

496746

Source:http://linkedlifedata.com/resource/pubmed/id/496746

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1979-12-18
pubmed:abstractText
Electroretinographic, optic chiasm, and visual cortex potentials were monitored in the awake guinea pig as nitrogen pressures were raised to 16 ATA and held for 30 min. Pressurization to 90 ATA with helium in 10-ATA increments followed. We sought to (a) quantify the depressant effect of nitrogen on the retina as compared to the central visual pathway, and (b) to test for pressure reversibility. The electroretinogram was reduced approximately 15%, the chiasm potential by 15%, and the cortical response by 32% in 16 ATA nitrogen, and latent periods for the three signals increased an average of 5-8%. Helium at pressure did not restore the amplitude of the electroretinogram or optic chiasm response, but the visual cortex potential returned to control levels near 90 ATA total pressure. Reversal of the nitrogen-induced latency increases by helium was partially effective up to 40 ATA. Control latent periods were not reached. Further attenuation of the electroretinogram and chiasm response amplitudes, and increased latencies of all signals were observed at 50-90 ATA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0095-6562
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
792-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Responses of retinal and visual pathway potentials of the guinea pig to nitrogen and helium at high pressure.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.