Linked Life Data

4959799

Source:http://linkedlifedata.com/resource/pubmed/id/4959799

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1967-4-11
pubmed:abstractText
Middleton, G. K., Jr. (Bowman Gray School of Medicine, Winston-Salem, N.C.), H. G. Cramblett, H. L. Moffet, J. P. Black, and H. Shulenberger. Micro diffusion precipitin tests for enteroviruses and influenza B virus. J. Bacteriol. 87:1171-1176. 1964.-A simple micro precipitin gel diffusion test has been adapted to the study of viral antigens. As far as is known from a review of recent literature, this is the first use of the ECHO viruses in precipitin tests and the first attempt to demonstrate by the gel diffusion technique precipitins in a patient's serum after natural virus infection rather than artificial immunization. The principal value of this technique in virology is the rapid identification or qualitative analysis of viral antigen preparations by use of pooled or specific hyperimmune sera. Virus concentrations of 10(7)tcid(50) per 0.1 ml are required for reliable results, but only 0.015 ml of serum is necessary for each test. Virus-serum precipitin reactions were type-specific except for reciprocal precipitation of ECHO 1 and ECHO 8 by their hyperimmune sera. No viral antigens have been found common to two or more virus types among those tested. Precipitins for viral antigens occur frequently in serum of patients after a viral infection and are readily detected by micro precipitin gel diffusion tests. However, this precipitin test remains at present a tool for virus and antigen identification and offers an approach for research appraisal of host response to infections.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13022978, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13035122, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13255879, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13340582, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13475622, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13507316, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13518182, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13541459, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13588200, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-13637042, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-14401082, http://linkedlifedata.com/resource/pubmed/commentcorrection/4959799-15402504
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1171-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1964
pubmed:articleTitle
Micro diffusion precipitin tests for enteroviruses and influenza B virus.
pubmed:publicationType
Journal Article