Linked Life Data

4950559

Source:http://linkedlifedata.com/resource/pubmed/id/4950559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1974-5-29
pubmed:abstractText
Examples of the biological occurrence of methyl ketones are reviewed. The lack of significant accumulations of these compounds in the biosphere indicates that a recycling of these organic molecules is occurring. Evidence for biodegradation of acetone by mammals and longer methyl ketones by microorganisms via terminal methyl-group oxidation is discussed. A new mechanism for the subterminal oxidation of methyl ketones by microorganisms is proposed whereby the first intermediate produced is an acetate ester which subsequently is cleaved to acetate and a primary alcohol two carbons shorter than the original ketone substrate. Methyl ketones can be produced by mammals and fungi by decarboxylation of beta-keto acids. Some bacteria are able to form methyl ketones via the oxidation of aliphatic hydrocarbons at the methylene carbon alpha to the methyl group. Speculations on the biosynthesis of methyl ketones by insects and plants and a discussion of the possible biological roles of methyl ketones in diverse biological systems are presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-2275
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
383-95
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
The biology of methyl ketones.
pubmed:publicationType
Journal Article, Comparative Study, Review