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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
|
pubmed:dateCreated |
1979-12-27
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pubmed:abstractText |
Nine medical centers collaborated in a prospective randomized study to evaluate prolonged extracorporeal membrane oxygenation (ECMO) as a therapy for severe acute respiratory failure (ARF). Ninety adult patients were selected by common criteria of arterial hypoxemia and treated with either conventional mechanical ventilation (48 patients) or mechanical ventilation supplemented with partial venoarterial bypass (42 patients). Four patients in each group survived. The majority of patients suffered acute bacterial or viral pneumonia (57%). All nine patients with pulmonary embolism and six patients with posttraumatic acute respiratory failure died. The majority of patients died of progressive reduction of transpulmonary gas exchange and decreased compliance due to diffuse pulmonary inflammation, necrosis, and fibrosis. We conclude that ECMO can support respiratory gas exchange but did not increase the probability of long-term survival in patients with severe ARF.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0098-7484
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pubmed:author |
pubmed-author:BagniewskiAA,
pubmed-author:BartlettR HRH,
pubmed-author:DrinkerP APA,
pubmed-author:EdmundsL HLH,
pubmed-author:FallatR JRJ,
pubmed-author:HillJ DJD,
pubmed-author:MillerR GRGJr,
pubmed-author:MorrisA HAH,
pubmed-author:PeirceE CEC2nd,
pubmed-author:PrattP CPC,
pubmed-author:ProctorH JHJ,
pubmed-author:SniderM TMT,
pubmed-author:ThomasA NAN,
pubmed-author:ZapolW MWM
|
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
242
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2193-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:490805-Acute Disease,
pubmed-meshheading:490805-Adult,
pubmed-meshheading:490805-Humans,
pubmed-meshheading:490805-Lung,
pubmed-meshheading:490805-Methods,
pubmed-meshheading:490805-Oxygenators, Membrane,
pubmed-meshheading:490805-Prospective Studies,
pubmed-meshheading:490805-Respiratory Insufficiency
|
pubmed:year |
1979
|
pubmed:articleTitle |
Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
|