Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1974-3-22
pubmed:abstractText
Cultures of Aedes albopictus cells persistently infected with wild-type Sindbis virus (SV-W) give rise to small plaque-forming mutants which are also temperature sensitive. These mutants, designated SV-C, are neutralized by antiserum produced against SV-W. Mutant ts clones were isolated from SV-C by plaque purification. After serial undiluted passage in BHK or mosquito cells, each of the clones gave rise to ts(+) revertants which, however, remained mutant with respect to plaque morphology. Nineteen of 20 clones derived from SV-C were RNA(+), and one was RNA(-) (SV-C-2). The RNA synthesizing activity, once induced in infected cells by SV-C-2, was stable at the nonpermissive temperature (39.5 C). All clones derived from SV-C were inactivated at 60 C much more quickly than was SV-W. It was not possible to demonstrate complementation between any of the SV-C clones.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-13360288, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-13571577, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-13931896, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4201188, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4301425, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4356681, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4386019, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4398081, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4550788, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4559687, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4734648, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4735592, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-4735935, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5062677, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5066350, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5137591, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5142327, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5817532, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5919228, http://linkedlifedata.com/resource/pubmed/commentcorrection/4855741-5919229
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-47
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:4855741-Aedes, pubmed-meshheading:4855741-Animals, pubmed-meshheading:4855741-Antigens, Viral, pubmed-meshheading:4855741-Cell Line, pubmed-meshheading:4855741-Chick Embryo, pubmed-meshheading:4855741-Cricetinae, pubmed-meshheading:4855741-Culture Techniques, pubmed-meshheading:4855741-Dactinomycin, pubmed-meshheading:4855741-Genetic Complementation Test, pubmed-meshheading:4855741-Genetic Variation, pubmed-meshheading:4855741-Hemagglutination Tests, pubmed-meshheading:4855741-Kidney, pubmed-meshheading:4855741-Mutation, pubmed-meshheading:4855741-Neutralization Tests, pubmed-meshheading:4855741-Phenotype, pubmed-meshheading:4855741-RNA, Viral, pubmed-meshheading:4855741-Sindbis Virus, pubmed-meshheading:4855741-Temperature, pubmed-meshheading:4855741-Tritium, pubmed-meshheading:4855741-Uridine, pubmed-meshheading:4855741-Viral Plaque Assay, pubmed-meshheading:4855741-Virus Cultivation
pubmed:year
1974
pubmed:articleTitle
Temperature-sensitive virus from Aedes albopictus cells chronically infected with Sindbis virus.
pubmed:publicationType
Journal Article